Thrombolytic therapy or surgery for valve prosthesis thrombosis: systematic review and meta-analysis

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Thrombolytic therapy or surgery for valve prosthesis thrombosis: systematic review and meta-analysis.

BACKGROUND Prosthetic heart valve thrombosis is a life-threatening condition for which treatment has not been evaluated by randomized trials. OBJECTIVES To compare surgery with thrombolytic therapy for the treatment of prosthetic valve thrombosis. METHODS A comprehensive systematic review was carried out by independent researchers using PubMed, Web of Knowledge, HINARI, LILACS and EMBASE, i...

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AIM Thrombolytic therapy induces faster clot dissolution than anticoagulation in patients with acute pulmonary embolism (PE) but is associated with an increased risk of haemorrhage. We reviewed the risks and benefits of thrombolytic therapy in the management of patients with acute PE. METHODS AND RESULTS We systematically reviewed randomized controlled studies comparing systemic thrombolytic ...

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ژورنال

عنوان ژورنال: Journal of Thrombosis and Haemostasis

سال: 2014

ISSN: 1538-7933

DOI: 10.1111/jth.12577